The Endocannabinoid System in human body, which helps regulated memory functions, appetite, energy balance and metabolism, stress responses, immune functions, female reproduction, the autonomic nervous system, analgesia, thermoregulation and sleep, comes with two types of receptors:
- Cannabinoid receptor type 1 (CB-1).
- Cannabinoid receptor type 2 (CB-2).
Once ingested, #Cannabis is broken down and results in the release of cannabinoids into the body. Cannabinoids in a person’s body become attracted to the two receptors CB1 & CB2 and then has an effect.
"In the actual activity of the endocannabinoids, it works on the presynaptic portions of the nerve. When cannabinoids attach to a receptor, the presynaptic region will release a compound that will attach to the postsynaptic receptor that will give you the effect you’re looking for. It tends to prevent release of the neurotransmitters." Dr. Christopher Prince said.
Unlike Opioids,Tylenol & #Aspirin which block the transmission of pain, Cannabis instead decreases the amount of pain transmission, which inhibits its ability to send a pain message to the brain. With a current lack of research, the efficacy of the pain inhibition is word of mouth at best, which Prince admits.
"Tylenol and Aspirin, in my opinion, are two of the most lethal painkillers out there, because you can self-medicate, and there’s no prescription required. They work well, but you start dealing with the abuse potential." He add.
Read full article Here ! And feel free to watch the video with Dr Alan Mandell, to learn about the adverse reactions that aspirin has to the body.